Selective Excision of AZTMP by Drug-Resistant Human Immunodeficiency Virus Reverse Transcriptase

Two distinct mechanisms can be envisioned for resistance of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to nucleoside analogs: one in which the mutations interfere with the ability of HIV-1 RT to incorporate the analog, and the other in which the mutations enhance the exci...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Boyer, Paul L., Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11312355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.10.4832-4842.2001
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