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Theoretical model of prion propagation: A misfolded protein induces misfolding

There is a hypothesis that dangerous diseases such as bovine spongiform encephalopathy, Creutzfeldt-Jakob, Alzheimer's, fatal familial insomnia, and several others are induced by propagation of wrong or misfolded conformations of some vital proteins. If for some reason the misfolded conformatio...

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Bibliografiske detaljer
Main Authors: Małolepsza, Edyta, Boniecki, Michał, Kolinski, Andrzej, Piela, Lucjan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142357/
https://ncbi.nlm.nih.gov/pubmed/15911770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409389102
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