Generation of a Highly Pathogenic Avian Influenza A Virus from an Avirulent Field Isolate by Passaging in Chickens

Highly virulent avian influenza viruses can arise from avirulent strains maintained in poultry, but evidence to support their generation from viruses in wild birds is lacking. The most likely mechanism for the acquisition of virulence by benign avian viruses is the introduction of mutations by error...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ito, Toshihiro, Goto, Hideo, Yamamoto, Eiji, Tanaka, Hiroko, Takeuchi, Mutsuko, Kuwayama, Masaru, Kawaoka, Yoshihiro, Otsuki, Koichi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4439-4443.2001
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