Recognition of N-Glycolylneuraminic Acid Linked to Galactose by the α2,3 Linkage Is Associated with Intestinal Replication of Influenza A Virus in Ducks

The hemagglutinin (HA) of H3 human influenza viruses does not support viral replication in duck intestine despite its avian origin. A Leu-to-Gln mutation at position 226 and a Ser-to-Gly mutation at position 228 in the HA of human A/Udorn/307/72 (H3N2) permit a reassortant virus [human Udorn HA, wit...

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Detalhes bibliográficos
Main Authors: Ito, Toshihiro, Suzuki, Yasuo, Suzuki, Takashi, Takada, Ayato, Horimoto, Taisuke, Wells, Krisna, Kida, Hiroshi, Otsuki, Koichi, Kiso, Makoto, Ishida, Hideharu, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102129/
https://ncbi.nlm.nih.gov/pubmed/10982377
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