Adaptation of Reovirus to Growth in the Presence of Protease Inhibitor E64 Segregates with a Mutation in the Carboxy Terminus of Viral Outer-Capsid Protein ς3

Reovirus virions are internalized into cells by receptor-mediated endocytosis. Within the endocytic compartment, the viral outer capsid undergoes acid-dependent proteolysis leading to degradation of ς3 protein and proteolytic cleavage of μ1/μ1C protein. E64 is a specific inhibitor of cysteine-contai...

Deskribapen osoa

Xehetasun bibliografikoak

Argitaratua izan da:	J Virol
Egile Nagusiak:	Ebert, Daniel H., Wetzel, J. Denise, Brumbaugh, David E., Chance, Stacey R., Stobie, Laura E., Baer, Geoffrey S., Dermody, Terence S.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2001
Gaiak:	Virus-Cell Interactions
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3197-3206.2001
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!