Vaccinia Virus Blocks Gamma Interferon Signal Transduction: Viral VH1 Phosphatase Reverses Stat1 Activation

We have analyzed the effects of vaccinia virus (VV) on gamma interferon (IFN-γ) signal transduction. Infection of cells with VV 1 to 2 h prior to treatment with IFN-γ inhibits phosphorylation and nuclear translocation of Stat1 and consequently blocks accumulation of mRNAs normally induced by IFN-γ....

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Najarro, Pilar, Traktman, Paula, Lewis, John A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238845/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3185-3196.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!