Temperature-sensitive vaccinia virus mutants identify a gene with an essential role in viral replication.

Vaccinia virus mutants ts2 and ts25, members of the same complementation group, exhibit a temperature-dependent arrest at the stage of viral DNA replication. The lesions responsible for the mutant phenotypes have been localized to the far left region of the HindIII B genomic fragment by marker rescu...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Rempel, R E, Anderson, M K, Evans, E, Traktman, P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249146/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.574-583.1990
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