In Vivo HP1 Targeting Causes Large-Scale Chromatin Condensation and Enhanced Histone Lysine Methylation

Changes in chromatin structure are a key aspect in the epigenetic regulation of gene expression. We have used a lac operator array system to visualize by light microscopy the effect of heterochromatin protein 1 (HP1) α (HP1α) and HP1β on large-scale chromatin structure in living mammalian cells. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Verschure, Pernette J., van der Kraan, Ineke, de Leeuw, Wim, van der Vlag, Johan, Carpenter, Anne E., Belmont, Andrew S., van Driel, Roel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2005
Pynciau:
Chromosome Structure and Dynamics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140641/
https://ncbi.nlm.nih.gov/pubmed/15899859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4552-4564.2005
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