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Condensed chromatin domains in the mammalian nucleus are accessible to large macromolecules

Most chromatin in interphase nuclei is part of condensed chromatin domains. Previous work has indicated that transcription takes place predominantly at the surface of chromatin domains, that is, in the perichromatin region. It is possible that genes inside chromatin domains are silenced due to inacc...

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Autores principales: Verschure, Pernette J., van der Kraan, Ineke, Manders, Erik M.M., Hoogstraten, Deborah, Houtsmuller, Adriaan B., van Driel, Roel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326359/
https://ncbi.nlm.nih.gov/pubmed/12947417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor922
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