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Condensed chromatin domains in the mammalian nucleus are accessible to large macromolecules

Most chromatin in interphase nuclei is part of condensed chromatin domains. Previous work has indicated that transcription takes place predominantly at the surface of chromatin domains, that is, in the perichromatin region. It is possible that genes inside chromatin domains are silenced due to inacc...

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Detalhes bibliográficos
Main Authors: Verschure, Pernette J., van der Kraan, Ineke, Manders, Erik M.M., Hoogstraten, Deborah, Houtsmuller, Adriaan B., van Driel, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326359/
https://ncbi.nlm.nih.gov/pubmed/12947417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor922
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