A Role for MeCP2 in Switching Gene Activity via Chromatin Unfolding and HP1γ Displacement

Methyl-CpG-binding protein 2 (MeCP2) is generally considered to act as a transcriptional repressor, whereas recent studies suggest that MeCP2 is also involved in transcription activation. To gain insight into this dual function of MeCP2, we assessed the impact of MeCP2 on higher-order chromatin stru...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Brink, Maartje C., Piebes, Diewertje G. E., de Groote, Marloes L., Luijsterburg, Martijn S., Casas-Delucchi, Corella S., van Driel, Roel, Rots, Marianne G., Cardoso, M. Cristina, Verschure, Pernette J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720725/
https://ncbi.nlm.nih.gov/pubmed/23935992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069347
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados