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Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization

Heterochromatic regions represent a significant portion of the mammalian genome and have been implied in several important cellular processes, including cell division and genomic stability. However, its composition and dynamics remain largely unknown. To better understand how heterochromatin functio...

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Detalhes bibliográficos
Main Authors: Casas-Delucchi, Corella S., Becker, Annette, Bolius, Janine J., Cardoso, M. Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526307/
https://ncbi.nlm.nih.gov/pubmed/22923521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks784
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