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Population Pharmacokinetics of Abacavir in Plasma and Cerebrospinal Fluid
The distribution of abacavir into the cerebrospinal fluid (CSF) was assessed by use of a population pharmacokinetic analysis. Plasma and CSF abacavir concentrations in 54 subjects were determined. The abacavir CSF/plasma ratio averaged 36% and increased throughout the dose interval. Abacavir penetra...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140502/ https://ncbi.nlm.nih.gov/pubmed/15917556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2504-2506.2005 |
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