The vhs1 Mutant Form of Herpes Simplex Virus Virion Host Shutoff Protein Retains Significant Internal Ribosome Entry Site-Directed RNA Cleavage Activity

The virion host shutoff (vhs) protein of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated turnover of host and viral mRNAs during HSV infection. As well, it induces endoribonucleolytic cleavage of RNA substrates when produced in a rabbit reticulocyte lysat...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lu, Patricia, Saffran, Holly A., Smiley, James R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.1072-1076.2001
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