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The vhs1 Mutant Form of Herpes Simplex Virus Virion Host Shutoff Protein Retains Significant Internal Ribosome Entry Site-Directed RNA Cleavage Activity

The virion host shutoff (vhs) protein of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated turnover of host and viral mRNAs during HSV infection. As well, it induces endoribonucleolytic cleavage of RNA substrates when produced in a rabbit reticulocyte lysat...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Lu, Patricia, Saffran, Holly A., Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2001
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.1072-1076.2001
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