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Strict Control of Human Immunodeficiency Virus Type 1 Replication by a Genetic Switch: Tet for Tat

Live-attenuated human immunodeficiency virus type 1 (HIV-1) variants have shown great promise as AIDS vaccines, but continued replication can lead to the selection of faster-replicating variants that are pathogenic. We therefore designed HIV-1 genomes that replicate exclusively upon addition of the...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Verhoef, Koen, Marzio, Giuseppe, Hillen, Wolfgang, Bujard, Hermann, Berkhout, Ben
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113994/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.979-987.2001
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