Efficient Human Immunodeficiency Virus Replication Requires a Fine-Tuned Level of Transcription

Transcription represents a crucial step in the life cycle of human immunodeficiency virus (HIV) and is highly regulated. Here we show that the strength of the viral long terminal repeat (LTR) promoter is optimized for efficient replication. Artificially increasing the rate of LTR-driven transcriptio...

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Detalhes bibliográficos
Main Authors: Marzio, Giuseppe, Vink, Monique, Verhoef, Koen, de Ronde, Anthony, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135974/
https://ncbi.nlm.nih.gov/pubmed/11861878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.6.3084-3088.2002
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