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Efficient Human Immunodeficiency Virus Replication Requires a Fine-Tuned Level of Transcription

Transcription represents a crucial step in the life cycle of human immunodeficiency virus (HIV) and is highly regulated. Here we show that the strength of the viral long terminal repeat (LTR) promoter is optimized for efficient replication. Artificially increasing the rate of LTR-driven transcriptio...

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Udgivet i:J Virol
Principais autores: Marzio, Giuseppe, Vink, Monique, Verhoef, Koen, de Ronde, Anthony, Berkhout, Ben
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861878/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.6.3084-3088.2002
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