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Human Immunodeficiency Virus Type 1 Protease Regulation of Tat Activity Is Essential for Efficient Reverse Transcription and Replication

The human immunodeficiency virus type 1 (HIV-1) Tat protein enhances reverse transcription, but it is not known whether Tat acts directly on the reverse transcription complex or through indirect mechanisms. Since processing of Tat by HIV protease (PR) might mask its presence and, at least in part, e...

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Detalles Bibliográficos
Main Authors: Apolloni, Ann, Hooker, C. William, Mak, Johnson, Harrich, David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC224567/
https://ncbi.nlm.nih.gov/pubmed/12941901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9912-9921.2003
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