Human Immunodeficiency Virus Type 1 Protease Regulation of Tat Activity Is Essential for Efficient Reverse Transcription and Replication

The human immunodeficiency virus type 1 (HIV-1) Tat protein enhances reverse transcription, but it is not known whether Tat acts directly on the reverse transcription complex or through indirect mechanisms. Since processing of Tat by HIV protease (PR) might mask its presence and, at least in part, e...

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Hlavní autoři: Apolloni, Ann, Hooker, C. William, Mak, Johnson, Harrich, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC224567/
https://ncbi.nlm.nih.gov/pubmed/12941901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9912-9921.2003
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