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Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Target Distinct Phases of Early Reverse Transcription

Early HIV-1 reverse transcription can be separated into initiation and elongation phases. Here we show, using PCR analysis of negative-strand strong-stop DNA [(−)ssDNA] synthesis in intact virus, that different reverse transcriptase (RT) inhibitors affect distinct phases of early natural endogenous...

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Detalhes bibliográficos
Main Authors: Hooker, C. William, Lott, William B., Harrich, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114103/
https://ncbi.nlm.nih.gov/pubmed/11238836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3095-3104.2001
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