Control of IL-2Rα gene expression: structural changes within the proximal enhancer/core promoter during T-cell development

During T-cell development in thymus, CD25, the IL-2 receptor α chain (IL-2Rα) is already expressed in early double-negative (DN) thymocytes where commitment to T-cell lineage has been established, but subsequently IL-2Rα is dramatically down-regulated for the remainder of T-cell development. The los...

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Библиографические подробности
Главные авторы: Yeh, Jung-Hua, Spicuglia, Salvatore, Kumar, Sanjeex, Sanchez-Sevilla, Albert, Ferrier, Pierre, Imbert, Jean
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2002
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC113837/
https://ncbi.nlm.nih.gov/pubmed/11972331
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