Novel CD28-Responsive Enhancer Activated by CREB/ATF and AP-1 Families in the Human Interleukin-2 Receptor α-Chain Locus

The interaction of interleukin-2 (IL-2) with its receptor (IL-2R) critically regulates the T-cell immune response, and the α chain CD25/IL-2Rα is required for the formation of the high-affinity receptor. Tissue-specific, inducible expression of the IL-2Rα gene is regulated by at least three positive...

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Detalles Bibliográficos
Autores principales: Yeh, Jung-Hua, Lecine, Patrick, Nunes, Jacques A., Spicuglia, Salvatore, Ferrier, Pierre, Olive, Daniel, Imbert, Jean
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC87111/
https://ncbi.nlm.nih.gov/pubmed/11416131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4515-4527.2001
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