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Control of IL-2Rα gene expression: structural changes within the proximal enhancer/core promoter during T-cell development
During T-cell development in thymus, CD25, the IL-2 receptor α chain (IL-2Rα) is already expressed in early double-negative (DN) thymocytes where commitment to T-cell lineage has been established, but subsequently IL-2Rα is dramatically down-regulated for the remainder of T-cell development. The los...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC113837/ https://ncbi.nlm.nih.gov/pubmed/11972331 |
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