The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor.

Lignende værker

• Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hot spots at sites of cytosine methylation in Escherichia coli.
  af: Wyszynski, M, et al.
  Udgivet: (1994)
• Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine.
  af: Santi, D V, et al.
  Udgivet: (1984)
• Methylation inhibitors can increase the rate of cytosine deamination by (cytosine-5)-DNA methyltransferase.
  af: Zingg, J M, et al.
  Udgivet: (1996)
• The cysteine conserved among DNA cytosine methylases is required for methyl transfer, but not for specific DNA binding.
  af: Wyszynski, M W, et al.
  Udgivet: (1993)
• Methylation of slipped duplexes, snapbacks and cruciforms by human DNA(cytosine-5)methyltransferase.
  af: Laayoun, A, et al.
  Udgivet: (1995)