The cysteine conserved among DNA cytosine methylases is required for methyl transfer, but not for specific DNA binding.

All DNA (cytosine-5)-methyltransferases contain a single conserved cysteine. It has been proposed that this cysteine initiates catalysis by attacking the C6 of cytosine and thereby activating the normally inert C5 position. We show here that substitutions of this cysteine in the E. coli methylase M....

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Bibliografiska uppgifter
Huvudupphovsmän: Wyszynski, M W, Gabbara, S, Kubareva, E A, Romanova, E A, Oretskaya, T S, Gromova, E S, Shabarova, Z A, Bhagwat, A S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC309106/
https://ncbi.nlm.nih.gov/pubmed/8441637
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