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Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine.

DNA containing 5-azacytosine (azaC) has previously been shown to be a potent inhibitor of DNA-cytosine methyltransferases. In this report, we describe experiments which demonstrate that azaC-DNA forms a covalent complex with Hpa II methylase, a bacterial enzyme that methylates the internal C of C-C-...

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Detalhes bibliográficos
Main Authors: Santi, D V, Norment, A, Garrett, C E
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392062/
https://ncbi.nlm.nih.gov/pubmed/6209710
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