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Respiratory-deficient human fibroblasts exhibiting defective mitochondrial DNA replication.

We have characterized cultured skin fibroblasts from two siblings affected with a fatal mitochondrial disease caused by a nuclear genetic defect. Mitochondrial respiratory-chain function was severely decreased in these cells. Southern-blot analysis showed that the fibroblasts had reduced levels of m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bodnar, A G, Cooper, J M, Leonard, J V, Schapira, A H
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1995
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136332/
https://ncbi.nlm.nih.gov/pubmed/7848281
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