Retinoic acid directly stimulates osteoclastic bone resorption and gene expression of cathepsin K/OC-2.

Vitamin A metabolites such as all-trans-retinoic acid (all-trans-RA) affect several steps of metabolic processes in vertebrates. In the last few years, several studies have shown the effect of RA on bone formation and metabolism. However, mechanisms of its action still remain unclear, especially wit...

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Bibliographic Details
Main Authors: Saneshige, S, Mano, H, Tezuka, K, Kakudo, S, Mori, Y, Honda, Y, Itabashi, A, Yamada, T, Miyata, K, Hakeda, Y
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135691/
https://ncbi.nlm.nih.gov/pubmed/7639684
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