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Misfolded BiP is degraded by a proteasome-independent endoplasmic-reticulum-associated degradation pathway

Misfolded proteins are removed from the ER (endoplasmic reticulum) by retrotranslocation to the cytosol and degradation by the ubiquitin–proteasome system in a process designated ERAD (ER-associated degradation). Analysing the turnover of a misfolded form of the ER-resident chaperone BiP (heavy-chai...

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Detalhes bibliográficos
Main Authors: Donoso, Gerda, Herzog, Volker, Schmitz, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135023/
https://ncbi.nlm.nih.gov/pubmed/15610068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041312
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