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Misfolded BiP is degraded by a proteasome-independent endoplasmic-reticulum-associated degradation pathway
Misfolded proteins are removed from the ER (endoplasmic reticulum) by retrotranslocation to the cytosol and degradation by the ubiquitin–proteasome system in a process designated ERAD (ER-associated degradation). Analysing the turnover of a misfolded form of the ER-resident chaperone BiP (heavy-chai...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Portland Press Ltd.
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1135023/ https://ncbi.nlm.nih.gov/pubmed/15610068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041312 |
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