Shedding and γ-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43

CD43 is a transmembrane molecule that contains a 123-aminoacids-long cytoplasmic tail and a highly O-glycosylated extracellular domain of mucin type. Endogenous CD43 expressed in COLO 205, K562 and Jurkat cells revealed a membrane-associated, 20 kDa CD43-specific cytoplasmic tail fragment (CD43-CTF)...

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Main Authors: Andersson, Christian X., Fernandez-Rodriguez, Julia, Laos, Sirle, Baeckström, Dan, Haass, Christian, Hansson, Gunnar C.
格式: Artigo
語言:Inglês
出版: Portland Press Ltd. 2005
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134965/
https://ncbi.nlm.nih.gov/pubmed/15540986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041387
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