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Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands

CYP27A1 (sterol 27-hydroxylase) catalyses an important sterol elimination pathway in the human macrophage, and consequently may protect against atherosclerosis. We studied the expression and regulation of CYP27A1 in a human macrophage-like cell-line, THP-1, and primary HMDMs (human monocyte-derived...

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Detalles Bibliográficos
Main Authors: Quinn, Carmel M., Jessup, Wendy, Wong, Jenny, Kritharides, Leonard, Brown, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134759/
https://ncbi.nlm.nih.gov/pubmed/15533057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041776
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