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Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex

Peroxisome-proliferator activated receptor-γ (PPARγ) is a nuclear hormone receptor that forms a heterodimeric complex with retinoid X receptor-α (RXRα) to regulate transcription of genes involved in fatty acid storage and glucose metabolism. PPARγ is a target for pharmaceutical intervention in type...

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Publicado en:PLoS One
Autores principales: Lemkul, Justin A., Lewis, Stephanie N., Bassaganya-Riera, Josep, Bevan, David R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425662/
https://ncbi.nlm.nih.gov/pubmed/25954810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123984
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