Purification and properties of cytochrome P-450-dependent 14 alpha-sterol demethylase from Candida albicans.

The purification of cytochrome P-450-dependent 14 alpha-sterol demethylase (P-450DM) from the important opportunistic fungal pathogen, Candida albicans, is described. Optimal purification (875-fold) was achieved by extracting the cytochrome from microsomes with sodium cholate followed by hydroxyapat...

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Bibliographic Details
Main Authors: Hitchcock, C A, Dickinson, K, Brown, S B, Evans, E G, Adams, D J
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133465/
https://ncbi.nlm.nih.gov/pubmed/2556999
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