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Cytochrome P-450-dependent 14 alpha-demethylation of lanosterol in Candida albicans.

A novel assay for cytochrome P-450-dependent 14 alpha-sterol demethylase of the important opportunistic fungal pathogen, Candida albicans, is described. The enzyme was assayed in microsomal preparations (microsomes) by measuring the incorporation of [14C]lanosterol into (4,14)-desmethylated sterols....

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Bibliografische gegevens
Hoofdauteurs: Hitchcock, C A, Brown, S B, Evans, E G, Adams, D J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138703/
https://ncbi.nlm.nih.gov/pubmed/2669735
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