Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart.

Protein farnesyltransferase (FTase) catalyses the addition of a farnesyl group to a cysteine within the so-called 'CAAX box' at the C-terminus of various proteins. In the present paper we report purification of Saccharomyces cerevisiae FTase to near-homogeneity. This was accomplished by co...

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Detalles Bibliográficos
Main Authors: Gomez, R, Goodman, L E, Tripathy, S K, O'Rourke, E, Manne, V, Tamanoi, F
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132125/
https://ncbi.nlm.nih.gov/pubmed/8424764
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