Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity

Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase κ (Polκ) encoded by the DINB1 gene. Our recent studies have indicated that human Polκ is capable of both error-free and error-prone translesion DNA synthesis in vi...

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Bibliographic Details
Main Authors: Zhang, Yanbin, Yuan, Fenghua, Xin, Hua, Wu, Xiaohua, Rajpal, Deepak K., Yang, Danzhou, Wang, Zhigang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113146/
https://ncbi.nlm.nih.gov/pubmed/11058111
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