Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity
Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase κ (Polκ) encoded by the DINB1 gene. Our recent studies have indicated that human Polκ is capable of both error-free and error-prone translesion DNA synthesis in vi...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4147 |
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