Human DNA polymerase κ synthesizes DNA with extraordinarily low fidelity

Escherichia coli DNA polymerase IV encoded by the dinB gene is involved in untargeted mutagenesis. Its human homologue is DNA polymerase κ (Polκ) encoded by the DINB1 gene. Our recent studies have indicated that human Polκ is capable of both error-free and error-prone translesion DNA synthesis in vi...

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izdano v:	Nucleic Acids Res
Principais autores:	Zhang, Yanbin, Yuan, Fenghua, Xin, Hua, Wu, Xiaohua, Rajpal, Deepak K., Yang, Danzhou, Wang, Zhigang
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2000
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058111/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4147
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