Overexpression of Cyclin A Inhibits Augmentation of Recombinant Adeno-Associated Virus Transduction by the Adenovirus E4orf6 Protein

The 34-kDa product of adenovirus E4 region open reading frame 6 (E4orf6) dramatically enhances transduction by recombinant adeno-associated virus vectors (rAAV). This is achieved by promoting the conversion of incoming single-stranded viral genomes into transcriptionally competent duplex molecules....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Grifman, Mirta, Chen, Nancie N., Gao, Guang-ping, Cathomen, Toni, Wilson, James M., Weitzman, Matthew D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559315/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10010-10019.1999
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