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Overexpression of Cyclin A Inhibits Augmentation of Recombinant Adeno-Associated Virus Transduction by the Adenovirus E4orf6 Protein

The 34-kDa product of adenovirus E4 region open reading frame 6 (E4orf6) dramatically enhances transduction by recombinant adeno-associated virus vectors (rAAV). This is achieved by promoting the conversion of incoming single-stranded viral genomes into transcriptionally competent duplex molecules....

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Detalhes bibliográficos
Main Authors: Grifman, Mirta, Chen, Nancie N., Gao, Guang-ping, Cathomen, Toni, Wilson, James M., Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113052/
https://ncbi.nlm.nih.gov/pubmed/10559315
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