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Sumoylation induced by the Arf tumor suppressor: A p53-independent function

The mouse p19(Arf) protein has both p53-dependent and p53-independent tumor-suppressive activities. Arf triggers sumoylation of many cellular proteins, including Mdm2 and nucleophosmin (NPM/B23), with which p19(Arf) physically interacts in vivo, and this occurs equally well in cells expressing or la...

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Detalhes bibliográficos
Main Authors: Tago, Kenji, Chiocca, Susanna, Sherr, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129025/
https://ncbi.nlm.nih.gov/pubmed/15897463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502978102
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