The H Gene of Rodent Brain-Adapted Measles Virus Confers Neurovirulence to the Edmonston Vaccine Strain

Molecular determinants of neuropathogenesis have been shown to be present in the hemagglutinin (H) protein of measles virus (MV). An H gene insertion vector has been generated from the Edmonston B vaccine full-length infectious clone of MV. Using this vector, it is possible to insert complete H open...

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Autores principales: Duprex, W. Paul, Duffy, Iain, McQuaid, Stephen, Hamill, Louise, Cosby, S. Louise, Billeter, Martin A., Schneider-Schaulies, Jürgen, ter Meulen, Volker, Rima, Bert K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC112776/
https://ncbi.nlm.nih.gov/pubmed/10400789
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