Extent of Measles Virus Spread and Immune Suppression Differentiates between Wild-Type and Vaccine Strains in the Cotton Rat Model (Sigmodon hispidus)

Infection of humans with wild-type measles virus leads to strong immune suppression and secondary infections, whereas immunization with an attenuated vaccine strain does not. Using the cotton rat model (Sigmodon hispidus), we investigated whether vaccine and wild-type viruses differ in viral spread...

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Detalhes bibliográficos
Main Authors: Pfeuffer, Joanna, Püschel, Karen, Meulen, Volker ter, Schneider-Schaulies, Jürgen, Niewiesk, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140581/
https://ncbi.nlm.nih.gov/pubmed/12477820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.150-158.2003
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