Extent of Measles Virus Spread and Immune Suppression Differentiates between Wild-Type and Vaccine Strains in the Cotton Rat Model (Sigmodon hispidus)

Infection of humans with wild-type measles virus leads to strong immune suppression and secondary infections, whereas immunization with an attenuated vaccine strain does not. Using the cotton rat model (Sigmodon hispidus), we investigated whether vaccine and wild-type viruses differ in viral spread...

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Bibliografiske detaljer
Main Authors: Pfeuffer, Joanna, Püschel, Karen, Meulen, Volker ter, Schneider-Schaulies, Jürgen, Niewiesk, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC140581/
https://ncbi.nlm.nih.gov/pubmed/12477820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.150-158.2003
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