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Extent of Measles Virus Spread and Immune Suppression Differentiates between Wild-Type and Vaccine Strains in the Cotton Rat Model (Sigmodon hispidus)

Infection of humans with wild-type measles virus leads to strong immune suppression and secondary infections, whereas immunization with an attenuated vaccine strain does not. Using the cotton rat model (Sigmodon hispidus), we investigated whether vaccine and wild-type viruses differ in viral spread...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Pfeuffer, Joanna, Püschel, Karen, Meulen, Volker ter, Schneider-Schaulies, Jürgen, Niewiesk, Stefan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140581/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477820/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.150-158.2003
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