Hemagglutinin Protein of Wild-Type Measles Virus Activates Toll-Like Receptor 2 Signaling

Pattern recognition via Toll-like receptors (TLR) by antigen-presenting cells is an important element of innate immunity. We report that wild-type measles virus but not vaccine strains activate cells via both human and murine TLR2, and this is a property of the hemagglutinin (H) protein. The ability...

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Detalhes bibliográficos
Main Authors: Bieback, Karen, Lien, Egil, Klagge, Ingo M., Avota, Elita, Schneider-Schaulies, Jürgen, Duprex, W. Paul, Wagner, Herrmann, Kirschning, Carsten J., ter Meulen, Volker, Schneider-Schaulies, Sibylle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136986/
https://ncbi.nlm.nih.gov/pubmed/12163593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8729-8736.2002
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