A Monomeric GTPase-Negative MxA Mutant with Antiviral Activity

MxA is a large, interferon-induced GTPase with antiviral activity against RNA viruses. It forms large oligomers, but whether oligomerization and GTPase activity are important for antiviral function is not known. The mutant protein MxA(L612K) carries a lysine-for-leucine substitution at position 612...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Janzen, Christian, Kochs, Georg, Haller, Otto
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Virus-Cell Interactions
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.8202-8206.2000
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