A Monomeric GTPase-Negative MxA Mutant with Antiviral Activity
MxA is a large, interferon-induced GTPase with antiviral activity against RNA viruses. It forms large oligomers, but whether oligomerization and GTPase activity are important for antiviral function is not known. The mutant protein MxA(L612K) carries a lysine-for-leucine substitution at position 612...
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| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10933733/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.17.8202-8206.2000 |
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