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Induction of p53-Independent Apoptosis by the Adenovirus E4orf4 Protein Requires Binding to the Bα Subunit of Protein Phosphatase 2A

Previous studies have indicated that the E4orf4 protein of human adenovirus type 2 (Ad2) induces p53-independent apoptosis. We believe that this process may play a role in cell death and viral spread at the final stages of productive infection. E4orf4 may also be of therapeutic value in treating som...

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Hlavní autoři: Marcellus, Richard C., Chan, Helen, Paquette, Denis, Thirlwell, Sarah, Boivin, Dominique, Branton, Philip E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC112317/
https://ncbi.nlm.nih.gov/pubmed/10933694
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